Supramolecular Medicinal Chemistry and Chemical Biology

Jayawickramarajah, J.; Wilson, A. Supramolecular Medicinal Chemistry and Chemical Biology. In Comprehensive Supramolecular Chemistry II; Elsevier, 2017; Vol. 5, p. 1.

Abstract

Supramolecular Chemistry takes significant inspiration from nature, with common terms that populate the introduction to many original articles including biomimetic, bioinspired, and the like. This is to be expected given the diversity of structure and function prevalent in the biological playground that arises as a consequence of noncovalent structure. Thus, to replicate biology with designed synthetic systems and to intervene in biological systems should be seen as a major objective in supramolecular chemistry along the road toward the ultimate goal of creating functional architecture(s) not found in nature. The companion volume to this—Bioinspired and Biomimetic Supramolecular Chemistry—includes inter alia chapters describing the community’s efforts to reproduce biology with model systems whereas this volume—Supramolecular Medicinal Chemistry and Chemical Biology—describes the progress made in exploiting our collective knowledge of supramolecular chemistry to intervene in biological systems and/or control materials behavior through well-refined understanding of noncovalent chemistry to achieve therapeutic or diagnostic benefit.

Last updated on 07/05/2024