We have successfully applied the i-QATT technique to measure blood coagulation in plasma samples collected from rodents (mice). Particularly, our analysis revealed hypercoagulability associated with increased fibrin activity in eNOS-deficient mice (vascular dementia model) infected with SARS-CoV-2. This collaborative work with Dr. Gregory Bix's lab has been published in Viruses. With its small sample volume requirement, acoustic tweezing coagulometry offers a unique opportunity to bridge in vivo and clinical studies of blood coagulation.
