Abstract
Supramolecular chemists find themselves working evermore at the intersection of chemistry and biology. Indeed, a key aim in contemporary supramolecular chemistry is to address salient problems associated with malfunctioning biological macromolecules (biomacromolecules). Hence, this volume provides a timely overview on the fundamental supramolecular chemistry aspects of selectively binding to, and inhibiting the function of, (deoxy)ribonucleic acids (DNA/RNA) and proteins—Companion volume 5 explores the medicinal aspects and ramifications of such interactions in greater detail. Furthermore, supramolecular chemists are traversing a two-way street (i.e., in conjunction to developing systems that interact with biomacromolecules), the field also takes much inspiration from the elegant structure, assembly states, and function of nature’s highly evolved biomacromolecules. As such, this volume also provides a series of reviews on self-assemblies and nanomaterials inspired from a signature biological context. These articles serve to illustrate how supramolecular chemists are leading the charge in harnessing the programmable conformations, self-assembly, and molecular recognition capacities of biomacromolecules or their synthetic congeners for applications ranging from materials to medicine.